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Ammonium Gemini Surfactants Form Complexes with Model Oligomers of siRNA and dsDNA
Dimeric cationic surfactants (gemini-type) are a group of amphiphilic compounds with potential use in gene therapy as effective carriers for nucleic acid transfection (i.e., siRNA, DNA, and plasmid DNA). Our studies have shown the formation of lipoplexes composed of alkanediyl-α,ω-bis[(oxymethyl)dim...
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| Publicado no: | Int J Mol Sci |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6887939/ https://ncbi.nlm.nih.gov/pubmed/31703275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20225546 |
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