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Xeroderma pigmentosum: overview of pharmacology and novel therapeutic strategies for neurological symptoms

Xeroderma pigmentosum (XP) encompasses a group of rare diseases characterized in most cases by malfunction of nucleotide excision repair (NER), which results in an increased sensitivity to UV radiation in affected individuals. Approximately 25–30% of XP patients present with neurological symptoms, s...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Br J Pharmacol
Hauptverfasser: Abeti, Rosella, Zeitlberger, Anna, Peelo, Colm, Fassihi, Hiva, Sarkany, Robert P E, Lehmann, Alan R, Giunti, Paola
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6887903/
https://ncbi.nlm.nih.gov/pubmed/30499105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14557
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