Oxidation Products of 5-Methylcytosine are Decreased in Senescent Cells and Tissues of Progeroid Mice

5-Hydroxymethylcytosine and 5-formylcytosine are stable DNA base modifications generated from 5-methylcytosine by the ten-eleven translocation protein family that function as epigenetic markers. 5-Hydroxymethyluracil may also be generated from thymine by ten-eleven translocation enzymes. Here, we as...

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Detalhes bibliográficos
Publicado no:J Gerontol A Biol Sci Med Sci
Main Authors: Zarakowska, Ewelina, Czerwinska, Jolanta, Tupalska, Agnieszka, Yousefzadeh, Matt J, Gregg, Siobhán Q, Croix, Claudette M St, Niedernhofer, Laura J, Foksinski, Marek, Gackowski, Daniel, Szpila, Anna, Starczak, Marta, Tudek, Barbara, Olinski, Ryszard
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
The Journal of Gerontology: Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6887695/
https://ncbi.nlm.nih.gov/pubmed/29415265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/gly012
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