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Novel frameshift mutation causes early termination of the thyroxine-binding globulin protein and complete thyroxine-binding globulin deficiency in a Chinese family: A case report

BACKGROUND: Thyroxine-binding globulin (TBG; the gene product of SERPINA7) is the main transporter of thyroid hormones in humans. Mutations in the TBG gene may lead to inherited TBG deficiency. There have been 28 reported mutations that associate with complete TBG deficiency (TBG-CD). Here we identi...

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Dades bibliogràfiques
Publicat a:World J Clin Cases
Autors principals: Dang, Ping-Ping, Xiao, Wei-Wei, Shan, Zhong-Yan, Xi, Yue, Wang, Ran-Ran, Yu, Xiao-Hui, Teng, Wei-Ping, Teng, Xiao-Chun
Format: Artigo
Idioma:Inglês
Publicat: Baishideng Publishing Group Inc 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6887617/
https://ncbi.nlm.nih.gov/pubmed/31799319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12998/wjcc.v7.i22.3887
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