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A series of Notch3 mutations in CADASIL; insights from 3D molecular modelling and evolutionary analyses
CADASIL disease belongs to the group of rare diseases. It is well established that the Notch3 protein is primarily responsible for the development of CADASIL syndrome. Herein, we attempt to shed light to the actual molecular mechanism underlying CADASIL via insights that we have from preliminary in...
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| Publicado no: | J Mol Biochem |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6887539/ https://ncbi.nlm.nih.gov/pubmed/31799216 |
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