The AAA+ ATPase RUVBL2 is essential for the oncogenic function of c-MYB in acute myeloid leukemia

Subtype-specific leukemia oncogenes drive aberrant gene expression profiles that converge on common essential mediators to ensure leukemia self-renewal and inhibition of differentiation. The transcription factor c-MYB functions as one such mediator in a diverse range of leukemias. Here we show for t...

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Detalhes bibliográficos
Publicado no:Leukemia
Main Authors: Armenteros-Monterroso, Elena, Zhao, Lu, Gasparoli, Luca, Brooks, Tony, Pearce, Kerra, Mansour, Marc R., Martens, Joost H.A., de Boer, Jasper, Williams, Owen
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6887538/
https://ncbi.nlm.nih.gov/pubmed/31138842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-019-0495-8
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