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Excitatory neurons are more disinhibited than inhibitory neurons by chloride dysregulation in the spinal dorsal horn

Neuropathic pain is a debilitating condition caused by the abnormal processing of somatosensory input. Synaptic inhibition in the spinal dorsal horn plays a key role in that processing. Mechanical allodynia – the misperception of light touch as painful – occurs when inhibition is compromised. Disinh...

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Veröffentlicht in:eLife
Hauptverfasser: Lee, Kwan Yeop, Ratté, Stéphanie, Prescott, Steven A
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6887484/
https://ncbi.nlm.nih.gov/pubmed/31742556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.49753
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