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Vemurafenib as first-line therapy in BRAF-V600E-mutant Erdheim-Chester disease with CNS involvement

Erdheim-Chester disease (ECD) is a rare histiocytosis that may affect the central nervous system (CNS). Infiltration by the disease occurs throughout the neuroaxis, usually involving the dentate nucleus and the pons, manifested as a pyramido-cerebellar syndrome. CNS involvement is an adverse prognos...

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Detalhes bibliográficos
Publicado no:BMJ Case Rep
Main Authors: Fernández-Eulate, Gorka, Muñoz-Lopetegi, Amaia, Ruiz, Irune, Urtasun, Miguel
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6887387/
https://ncbi.nlm.nih.gov/pubmed/31748352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bcr-2018-228280
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