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Lessons from animal models of endocrine disorders caused by defects of protein folding in the secretory pathway
Most peptide hormones originate from secretory protein precursors synthesized within the endoplasmic reticulum (ER). In this specialized organelle, the newly-made prohormones must fold to their native state. Completion of prohormone folding usually occurs prior to migration through the secretory pat...
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| Pubblicato in: | Mol Cell Endocrinol |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6886696/ https://ncbi.nlm.nih.gov/pubmed/31605742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2019.110613 |
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