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Simvastatin Evokes An Unpredicted Antagonism For Tamoxifen In MCF-7 Breast Cancer Cells

PURPOSE: Tamoxifen (TAM) is a non-steroidal antiestrogen drug, used in the prevention and treatment of all stages of hormone-responsive breast cancer. Simvastatin (SIM) is a lipid-lowering agent and has been shown to inhibit cancer cell growth. The study aimed to investigate the effect of the combin...

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Publicado en:Cancer Manag Res
Main Authors: Ibrahim, Amel B, Zaki, Hala F, Wadie, Walaa, Omran, Mervat M, Shouman, Samia A
Formato: Artigo
Idioma:Inglês
Publicado: Dove 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6886548/
https://ncbi.nlm.nih.gov/pubmed/31819634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S218668
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