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Crystal Structure of the Ligand-Binding Domain of a LysR-type Transcriptional Regulator: Transcriptional Activation via a Rotary Switch

LysR-type transcriptional regulators (LTTRs) generally bind to target promoters in two conformations, depending on the availability of inducing ligands. OccR is an LTTR that regulates the octopine catabolism operon of Agrobacterium tumefaciens. OccR binds to a site located between the divergent occQ...

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Detalhes bibliográficos
Publicado no:Mol Microbiol
Main Authors: Kim, Youngchang, Chhor, Gekleng, Tsai, Ching-Sung, Winans, James B., Jedrzejczak, Robert, Joachimiak, Andrzej, Winans, Stephen C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6886530/
https://ncbi.nlm.nih.gov/pubmed/30168204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.14115
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