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Senescence-accelerated mice (SAMP1/TA-1) treated repeatedly with lipopolysaccharide develop a condition that resembles hemophagocytic lymphohistiocytosis

Hemophagocytic lymphohistiocytosis is a life-threatening systemic hyperinflammatory disorder with primary and secondary forms. Primary hemophagocytic lymphohistiocytosis is associated with inherited defects in various genes that affect the immunological cytolytic pathway. Secondary hemophagocytic ly...

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Bibliographic Details
Published in:Haematologica
Main Authors: Tsuboi, Isao, Harada, Tomonori, Hirabayashi, Yoko, Aizawa, Shin
Format: Artigo
Language:Inglês
Published: Ferrata Storti Foundation 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6886438/
https://ncbi.nlm.nih.gov/pubmed/30819910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2018.209551
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