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Knockdown of mitofilin inhibits autophagy and facilitates starvation-induced apoptosis in HeLa cells

OBJECTIVE(S): Mitofilin contributes to the maintenance of mitochondrial structure and functions. This study was undertaken to determine the mechanisms underlying its regulation of apoptosis. MATERIALS AND METHODS: Mitofilin was knockdowned by specific short hairpin RNA (shRNA) and the stable HeLa ce...

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Vydáno v:Iran J Basic Med Sci
Hlavní autoři: Shen, Mengli, Wang, Li, Kuang, Lingyun, Liu, Danhui
Médium: Artigo
Jazyk:Inglês
Vydáno: Mashhad University of Medical Sciences 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6885394/
https://ncbi.nlm.nih.gov/pubmed/31998453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/ijbms.2019.36173.8617
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