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Knockdown of mitofilin inhibits autophagy and facilitates starvation-induced apoptosis in HeLa cells
OBJECTIVE(S): Mitofilin contributes to the maintenance of mitochondrial structure and functions. This study was undertaken to determine the mechanisms underlying its regulation of apoptosis. MATERIALS AND METHODS: Mitofilin was knockdowned by specific short hairpin RNA (shRNA) and the stable HeLa ce...
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| Veröffentlicht in: | Iran J Basic Med Sci |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Mashhad University of Medical Sciences
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6885394/ https://ncbi.nlm.nih.gov/pubmed/31998453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/ijbms.2019.36173.8617 |
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