Mitochondrial Oxidative Stress Impairs Energy Metabolism and Reduces Stress Resistance and Longevity of C. elegans

INTRODUCTION: Mitochondria supply cellular energy and are key regulators of intrinsic cell death and consequently affect longevity. The nematode Caenorhabditis elegans is frequently used for lifespan assays. Using paraquat (PQ) as a generator of reactive oxygen species, we here describe its effects...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Dilberger, Benjamin, Baumanns, Stefan, Schmitt, Fabian, Schmiedl, Tommy, Hardt, Martin, Wenzel, Uwe, Eckert, Gunter P.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6885289/
https://ncbi.nlm.nih.gov/pubmed/31827694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/6840540
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