Dnmt3a-Mediated DNA Methylation Changes Regulate Osteogenic Differentiation of hMSCs Cultivated in the 3D Scaffolds under Oxidative Stress

Oxidative stress (OS) caused by multiple factors occurs after the implantation of bone repair materials. DNA methylation plays an important role in the regulation of osteogenic differentiation. Moreover, recent studies suggest that DNA methyltransferases (Dnmts) are involved in bone formation and re...

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Détails bibliographiques
Publié dans:Oxid Med Cell Longev
Auteurs principaux: Li, Liangping, Ling, Zemin, Dong, Wenwu, Chen, Xiaoying, Vater, Corina, Liao, Hongxing, Qi, Qihua, Hu, Hao, Chen, Yan, Gelinsky, Michael, Stiehler, Maik, Zou, Xuenong
Format: Artigo
Langue:Inglês
Publié: Hindawi 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6885223/
https://ncbi.nlm.nih.gov/pubmed/31827676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/4824209
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