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Immune pressures drive the promoter hypermethylation of neoantigen genes

Cancer cells with strong immunogenicity are susceptible for elimination by cancer immunoediting, while the subpopulations with weak immunogenicity survive. As a result, a subset of cancer cells evade the immune attack and evolve into overt clinical lesions. During cancer evolution, it has been well...

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Detalhes bibliográficos
Publicado no:Exp Hematol Oncol
Main Authors: Yi, Ming, Dong, Bing, Chu, Qian, Wu, Kongming
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6884785/
https://ncbi.nlm.nih.gov/pubmed/31799063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40164-019-0156-7
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