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Fractionated head and neck irradiation impacts taste progenitors, differentiated taste cells, and Wnt/β-catenin signaling in adult mice

Head and neck cancer patients receiving conventional repeated, low dose radiotherapy (fractionated IR) suffer from taste dysfunction that can persist for months and often years after treatment. To understand the mechanisms underlying functional taste loss, we established a fractionated IR mouse mode...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gaillard, Dany, Shechtman, Lauren A., Millar, Sarah E., Barlow, Linda A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6884601/
https://ncbi.nlm.nih.gov/pubmed/31784592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54216-9
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