Characterization of novel, recurrent genomic rearrangements as sensitive MRD targets in childhood B-cell precursor ALL

B-cell precursor (BCP) ALL carry a variety of classical V(D)J rearrangements as well as genomic fusions and translocations. Here, we assessed the value of genomic capture high-throughput sequencing (gc-HTS) in BCP ALL (n = 183) for the identification and implementation of targets for minimal residua...

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Vydáno v:Blood Cancer J
Hlavní autoři: zur Stadt, Udo, Alawi, Malik, Adao, Manuela, Indenbirken, Daniela, Escherich, Gabriele, Horstmann, Martin A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6884523/
https://ncbi.nlm.nih.gov/pubmed/31784504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41408-019-0257-x
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