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Differences in blastomere totipotency in 2-cell mouse embryos are a maternal trait mediated by asymmetric mRNA distribution

It is widely held that the first two blastomeres of mammalian embryos are equally totipotent and that this totipotency belongs to the group of regulative properties. However, this interpretation neglects an important aspect: evidence only came from successful monozygotic twins which can speak only f...

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Detalhes bibliográficos
Publicado no:Mol Hum Reprod
Main Authors: Casser, E, Wdowik, S, Israel, S, Witten, A, Schlatt, S, Nordhoff, V, Boiani, M
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6884417/
https://ncbi.nlm.nih.gov/pubmed/31504820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molehr/gaz051
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