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The Impact of Pathway Database Choice on Statistical Enrichment Analysis and Predictive Modeling

Pathway-centric approaches are widely used to interpret and contextualize -omics data. However, databases contain different representations of the same biological pathway, which may lead to different results of statistical enrichment analysis and predictive models in the context of precision medicin...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Mubeen, Sarah, Hoyt, Charles Tapley, Gemünd, André, Hofmann-Apitius, Martin, Fröhlich, Holger, Domingo-Fernández, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6883970/
https://ncbi.nlm.nih.gov/pubmed/31824580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.01203
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