Metabolomic Assessment Reveals Alteration in Polyols and Branched Chain Amino Acids Associated With Present and Future Renal Impairment in a Discovery Cohort of 637 Persons With Type 1 Diabetes

Background: Improved understanding of the pathophysiology causing diabetic kidney disease (DKD) is imperative. The aim of this study was to uncover associations between serum metabolites and renal outcomes. Methods: Non-targeted serum metabolomics analyses were performed in samples from 637 persons...

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Detalhes bibliográficos
Publicado no:Front Endocrinol (Lausanne)
Main Authors: Tofte, Nete, Suvitaival, Tommi, Trost, Kajetan, Mattila, Ismo Matias, Theilade, Simone, Winther, Signe Abitz, Ahluwalia, Tarunveer Singh, Frimodt-Møller, Marie, Legido-Quigley, Cristina, Rossing, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Endocrinology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6883958/
https://ncbi.nlm.nih.gov/pubmed/31824430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2019.00818
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