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Pubertal stress recalibration reverses the effects of early life stress in postinstitutionalized children

Nonhuman animal models reveal that the hypothalamic–pituitary–adrenocortical (HPA) axis calibrates to the harshness of the environment during a sensitive period in infancy. Humans exposed to depriving institutional care in infancy show reduced HPA axis responsivity, even years after they are placed...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Gunnar, Megan R., DePasquale, Carrie E., Reid, Brie M., Donzella, Bonny, Miller, Bradley S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6883847/
https://ncbi.nlm.nih.gov/pubmed/31712449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1909699116
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