A DNA virus-encoded immune antagonist fully masks the potent antiviral activity of RNAi in Drosophila

Coevolution of viruses and their hosts may lead to viral strategies to avoid, evade, or suppress antiviral immunity. An example is antiviral RNA interference (RNAi) in insects: the host RNAi machinery processes viral double-stranded RNA into small interfering RNAs (siRNAs) to suppress viral replicat...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Bronkhorst, Alfred W., Vogels, Rob, Overheul, Gijs J., Pennings, Bas, Gausson-Dorey, Valérie, Miesen, Pascal, van Rij, Ronald P.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2019
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6883776/
https://ncbi.nlm.nih.gov/pubmed/31712431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1909183116
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