Association of EGLN1 gene with high aerobic capacity of Peruvian Quechua at high altitude

Highland native Andeans have resided at altitude for millennia. They display high aerobic capacity (VO(2)max) at altitude, which may be a reflection of genetic adaptation to hypoxia. Previous genomewide (GW) scans for natural selection have nominated Egl-9 homolog 1 gene (EGLN1) as a candidate gene....

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Brutsaert, Tom D., Kiyamu, Melisa, Elias Revollendo, Gianpietro, Isherwood, Jenna L., Lee, Frank S., Rivera-Ch, Maria, Leon-Velarde, Fabiola, Ghosh, Sudipta, Bigham, Abigail W.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2019
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6883775/
https://ncbi.nlm.nih.gov/pubmed/31712437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1906171116
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