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Association of EGLN1 gene with high aerobic capacity of Peruvian Quechua at high altitude

Highland native Andeans have resided at altitude for millennia. They display high aerobic capacity (VO(2)max) at altitude, which may be a reflection of genetic adaptation to hypoxia. Previous genomewide (GW) scans for natural selection have nominated Egl-9 homolog 1 gene (EGLN1) as a candidate gene....

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Brutsaert, Tom D., Kiyamu, Melisa, Elias Revollendo, Gianpietro, Isherwood, Jenna L., Lee, Frank S., Rivera-Ch, Maria, Leon-Velarde, Fabiola, Ghosh, Sudipta, Bigham, Abigail W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6883775/
https://ncbi.nlm.nih.gov/pubmed/31712437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1906171116
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