Phosphoproteomic Landscaping Identifies Non-canonical cKIT Signaling in Polycythemia Vera Erythroid Progenitors

Although stem cell factor (SCF)/cKIT interaction plays key functions in erythropoiesis, cKIT signaling in human erythroid cells is still poorly defined. To provide new insights into cKIT-mediated erythroid expansion in development and disease, we performed phosphoproteomic profiling of primary eryth...

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Detalles Bibliográficos
Publicado en:Front Oncol
Autores principales: Federici, Giulia, Varricchio, Lilian, Martelli, Fabrizio, Falchi, Mario, Picconi, Orietta, Francescangeli, Federica, Contavalli, Paola, Girelli, Gabriella, Tafuri, Agostino, Petricoin, Emanuel F., Mazzarini, Maria, Zeuner, Ann, Migliaccio, Anna Rita
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6883719/
https://ncbi.nlm.nih.gov/pubmed/31824842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01245
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