Orotracheal treprostinil administration attenuates bleomycin-induced lung injury, vascular remodeling, and fibrosis in mice

Pulmonary fibrosis is a progressive disease characterized by disruption of lung architecture and deregulation of the pulmonary function. Prostacyclin, a metabolite of arachidonic acid, is a potential disease mediator since it exerts anti-inflammatory and anti-fibrotic actions. We investigated the ef...

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Vydáno v:Pulm Circ
Hlavní autoři: Nikitopoulou, Ioanna, Manitsopoulos, Nikolaos, Kotanidou, Anastasia, Tian, Xia, Petrovic, Aleksandar, Magkou, Christina, Ninou, Ioanna, Aidinis, Vassilis, Schermuly, Ralph T., Kosanovic, Djuro, Orfanos, Stylianos E.
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2019
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6883672/
https://ncbi.nlm.nih.gov/pubmed/31819797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2045894019881954
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