Systematic comparison of hUC-MSCs at various passages reveals the variations of signatures and therapeutic effect on acute graft-versus-host disease

BACKGROUND: Mesenchymal stem cells are heterogenous populations with hematopoietic supporting and immunomodulating capacities. Enormous studies have focused on their preclinical or clinical therapeutic effects, yet the systematic study of continuous in vitro passages on signatures and functions of U...

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Vydáno v:Stem Cell Res Ther
Hlavní autoři: Zhao, Qinjun, Zhang, Leisheng, Wei, Yimeng, Yu, Hao, Zou, Linglin, Huo, Jiali, Yang, Hongju, Song, Baoquan, Wei, Teng, Wu, Dan, Zhang, Wenxia, Zhang, Lei, Liu, Dengke, Li, Zongjin, Chi, Ying, Han, Zhibo, Han, Zhongchao
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6883552/
https://ncbi.nlm.nih.gov/pubmed/31779707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-019-1478-4
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