Safety and efficacy of a new micronized formulation of the ALIAmide palmitoylglucosamine in preclinical models of inflammation and osteoarthritis pain

BACKGROUND: Osteoarthritis is increasingly recognized as the result of a complex interplay between inflammation, chrondrodegeneration, and pain. Joint mast cells are considered to play a key role in orchestrating this detrimental triad. ALIAmides down-modulate mast cells and more generally hyperacti...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Cordaro, Marika, Siracusa, Rosalba, Impellizzeri, Daniela, D’ Amico, Ramona, Peritore, Alessio Filippo, Crupi, Rosalia, Gugliandolo, Enrico, Fusco, Roberta, Di Paola, Rosanna, Schievano, Carlo, Cuzzocrea, Salvatore
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6883534/
https://ncbi.nlm.nih.gov/pubmed/31779692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-019-2048-y
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