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Implications of product withdrawal on a post-approval pragmatic trial: The VOLUME study experience

INTRODUCTION: Many clinical trials terminate early due to safety and efficacy concerns, and less often due to unexpected “positive” findings. However, early termination of post-approval (Phase IV) pragmatic randomized trials for commercial reasons is less frequent, may be more complex, and may requi...

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Bibliografiske detaljer
Udgivet i:Contemp Clin Trials Commun
Main Authors: Kolitsopoulos, Francesca M., Gatto, Nicolle M., Sweetland, Kevin, Bracken, Michael B., Jackson, Neville
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6883292/
https://ncbi.nlm.nih.gov/pubmed/31799472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.conctc.2019.100477
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