Inflammation induced by incomplete radiofrequency ablation accelerates tumor progression and hinders PD-1 immunotherapy

Radiofrequency ablation (RFA) promotes tumor antigen-specific T cell responses and enhances the effect of immunotherapy in preclinical settings. Here we report that the existence of remnant tumor masses due to incomplete RFA (iRFA) is associated with earlier new metastases and poor survival in patie...

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Pubblicato in:Nat Commun
Autori principali: Shi, Liangrong, Wang, Junjun, Ding, Nianhua, Zhang, Yi, Zhu, Yibei, Dong, Shunli, Wang, Xiaohui, Peng, Changli, Zhou, Chunhui, Zhou, Ledu, Li, Xiaodong, Shi, Hongbing, Wu, Wei, Long, Xueyin, Wu, Changping, Liao, Weihua
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6883042/
https://ncbi.nlm.nih.gov/pubmed/31780645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13204-3
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