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Protodioscin protects PC12 cells against oxygen and glucose deprivation-induced injury through miR-124/AKT/Nrf2 pathway

The purpose of the current study was to demonstrate the neuroprotective effect of protodioscin (Prot) in an in vitro model of ischemia/reperfusion (I/R) and investigate the underlying molecular mechanism. After PC12 cells were exposed to oxygen and glucose deprivation (OGD) reperfusion, PI staining...

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Détails bibliographiques
Publié dans:Cell Stress Chaperones
Auteurs principaux: Shu, Kun, Zhang, Yuelin
Format: Artigo
Langue:Inglês
Publié: Springer Netherlands 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6882996/
https://ncbi.nlm.nih.gov/pubmed/31446555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-019-01031-w
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