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The Glucan-Remodeling Enzyme Phr1p and the Chitin Synthase Chs1p Cooperate to Maintain Proper Nuclear Segregation and Cell Integrity in Candida albicans

GH72 family of β-(1,3)-glucanosyltransferases is unique to fungi and is required for cell wall biogenesis, morphogenesis, virulence, and in some species is essential for life. Candida albicans PHR1 and PHR2 are pH-regulated genes that encode GH72 enzymes highly similar to Gas1p of Saccharomyces cere...

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Pubblicato in:Front Cell Infect Microbiol
Autori principali: Degani, Genny, Popolo, Laura
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6882867/
https://ncbi.nlm.nih.gov/pubmed/31824871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2019.00400
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