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Butyric acid, a gut bacteria metabolite, lowers arterial blood pressure via colon-vagus nerve signaling and GPR41/43 receptors

Butyric acid (BA) is a short-chain fatty acid (SCFA) produced by gut bacteria in the colon. We hypothesized that colon-derived BA may affect hemodynamics. Arterial blood pressure (BP) and heart rate (HR) were recorded in anesthetized, male, 14-week-old Wistar rats. A vehicle, BA, or 3-hydroxybutyrat...

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Detalhes bibliográficos
Publicado no:Pflugers Arch
Main Authors: Onyszkiewicz, Maksymilian, Gawrys-Kopczynska, Marta, Konopelski, Piotr, Aleksandrowicz, Marta, Sawicka, Aneta, Koźniewska, Ewa, Samborowska, Emilia, Ufnal, Marcin
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6882756/
https://ncbi.nlm.nih.gov/pubmed/31728701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-019-02322-y
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