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Oral delivery of lycopene-loaded microemulsion for brain-targeting: preparation, characterization, pharmacokinetic evaluation and tissue distribution

Lycopene is considered as a promising neuroprotector with multiple bioactivities, while its therapeutic use in neurological disorders is restricted due to low solubility, instability and limited bioavailability. Our work aimed to develop lycopene-loaded microemulsion (LME) and investigate its potent...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Drug Deliv
Main Authors: Guo, Yunliang, Mao, Xuyan, Zhang, Jing, Sun, Peng, Wang, Haiyang, Zhang, Yue, Ma, Yingjuan, Xu, Song, Lv, Renjun, Liu, Xueping
פורמט: Artigo
שפה:Inglês
יצא לאור: Taylor & Francis 2019
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6882477/
https://ncbi.nlm.nih.gov/pubmed/31738085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2019.1689312
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