Multiple Origins and Specific Evolution of CRISPR/Cas9 Systems in Minimal Bacteria (Mollicutes)

CRISPR/Cas systems provide adaptive defense mechanisms against invading nucleic acids in prokaryotes. Because of its interest as a genetic tool, the Type II CRISPR/Cas9 system from Streptococcus pyogenes has been extensively studied. It includes the Cas9 endonuclease that is dependent on a dual-guid...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Ipoutcha, Thomas, Tsarmpopoulos, Iason, Talenton, Vincent, Gaspin, Christine, Moisan, Annick, Walker, Caray A., Brownlie, Joe, Blanchard, Alain, Thebault, Patricia, Sirand-Pugnet, Pascal
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6882279/
https://ncbi.nlm.nih.gov/pubmed/31824468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.02701
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