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2D (2 Dimensional) TEQR design for Determining the optimal Dose for safety and efficacy
Designs, such as the Eff-Tox, OBD (optimal biological dose), STEIN (simple efficacy toxicity interval), and TEPI (toxicity efficacy probability interval) designs, have been proposed to determine the optimal dose of a new oncology drug using both efficacy and toxicity. The goal of these designs is to...
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Publicado no: | Contemp Clin Trials Commun |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Elsevier
2019
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6881644/ https://ncbi.nlm.nih.gov/pubmed/31799471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.conctc.2019.100461 |
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