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2D (2 Dimensional) TEQR design for Determining the optimal Dose for safety and efficacy
Designs, such as the Eff-Tox, OBD (optimal biological dose), STEIN (simple efficacy toxicity interval), and TEPI (toxicity efficacy probability interval) designs, have been proposed to determine the optimal dose of a new oncology drug using both efficacy and toxicity. The goal of these designs is to...
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| Publicat a: | Contemp Clin Trials Commun |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6881644/ https://ncbi.nlm.nih.gov/pubmed/31799471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.conctc.2019.100461 |
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