Advanced Glycation End-Products and Hyperglycemia Increase Angiopoietin-2 Production by Impairing Angiopoietin-1-Tie-2 System

The angiopoietin-Tie-2 system plays a crucial role in the maintenance of endothelial integrity. Hyperglycemia and advanced glycation end-products (AGEs) are involved in endothelial cell dysfunction responsible of the pathogenesis of microvascular complications of diabetes. Here, we investigated whet...

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Détails bibliographiques
Publié dans:J Diabetes Res
Auteurs principaux: Puddu, Alessandra, Sanguineti, Roberta, Maggi, Davide, Nicolò, Massimo, Traverso, Carlo E., Cordera, Renzo, Viviani, Giorgio L.
Format: Artigo
Langue:Inglês
Publié: Hindawi 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6881581/
https://ncbi.nlm.nih.gov/pubmed/31828164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/6198495
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