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RNA secondary structure prediction using an ensemble of two-dimensional deep neural networks and transfer learning

The majority of our human genome transcribes into noncoding RNAs with unknown structures and functions. Obtaining functional clues for noncoding RNAs requires accurate base-pairing or secondary-structure prediction. However, the performance of such predictions by current folding-based algorithms has...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Singh, Jaswinder, Hanson, Jack, Paliwal, Kuldip, Zhou, Yaoqi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6881452/
https://ncbi.nlm.nih.gov/pubmed/31776342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13395-9
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