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MKL1 promotes endothelial-to-mesenchymal transition and liver fibrosis by activating TWIST1 transcription
Excessive fibrogenic response in the liver disrupts normal hepatic anatomy and function heralding such end-stage liver diseases as hepatocellular carcinoma and cirrhosis. Sinusoidal endothelial cells contribute to myofibroblast activation and liver fibrosis by undergoing endothelial-mesenchymal tran...
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| Publicado no: | Cell Death Dis |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6881349/ https://ncbi.nlm.nih.gov/pubmed/31776330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-2101-4 |
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