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Cytoplasmic glycoengineering enables biosynthesis of nanoscale glycoprotein assemblies

Glycosylation of proteins profoundly impacts their physical and biological properties. Yet our ability to engineer novel glycoprotein structures remains limited. Established bacterial glycoengineering platforms require secretion of the acceptor protein to the periplasmic space and preassembly of the...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Tytgat, Hanne L. P., Lin, Chia-wei, Levasseur, Mikail D., Tomek, Markus B., Rutschmann, Christoph, Mock, Jacqueline, Liebscher, Nora, Terasaka, Naohiro, Azuma, Yusuke, Wetter, Michael, Bachmann, Martin F., Hilvert, Donald, Aebi, Markus, Keys, Timothy G.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6881330/
https://ncbi.nlm.nih.gov/pubmed/31776333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13283-2
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