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Immune Checkpoint Blockade – How Does It Work in Brain Metastases?

Immune checkpoints restrain the immune system following its activation and their inhibition unleashes anti-tumor immune responses. Immune checkpoint inhibitors revolutionized the treatment of several cancer types, including melanoma, and immune checkpoint blockade with anti-PD-1 and anti-CTLA-4 anti...

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Bibliografiske detaljer
Udgivet i:Front Mol Neurosci
Main Authors: Lorger, Mihaela, Andreou, Tereza, Fife, Christopher, James, Fiona
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6881300/
https://ncbi.nlm.nih.gov/pubmed/31824260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2019.00282
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