Contribution of Common Genetic Variants to Familial Aggregation of Disease and Implications for Sequencing Studies

Despite genetics being accepted as the primary cause of familial aggregation for most diseases, it is still unclear whether afflicted families are likely to share a single highly penetrant rare variant, many minimally penetrant common variants, or a combination of the two types of variants. We there...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:PLoS Genet
Main Authors: Schlafly, Andrew, Pfeiffer, Ruth M., Nagore, Eduardo, Puig, Susana, Calista, Donato, Ghiorzo, Paola, Menin, Chiara, Fargnoli, Maria Concetta, Peris, Ketty, Song, Lei, Zhang, Tongwu, Shi, Jianxin, Landi, Maria Teresa, Sampson, Joshua Neil
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2019
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6881075/
https://ncbi.nlm.nih.gov/pubmed/31730655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008490
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