Contribution of Common Genetic Variants to Familial Aggregation of Disease and Implications for Sequencing Studies

Despite genetics being accepted as the primary cause of familial aggregation for most diseases, it is still unclear whether afflicted families are likely to share a single highly penetrant rare variant, many minimally penetrant common variants, or a combination of the two types of variants. We there...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :PLoS Genet
Главные авторы: Schlafly, Andrew, Pfeiffer, Ruth M., Nagore, Eduardo, Puig, Susana, Calista, Donato, Ghiorzo, Paola, Menin, Chiara, Fargnoli, Maria Concetta, Peris, Ketty, Song, Lei, Zhang, Tongwu, Shi, Jianxin, Landi, Maria Teresa, Sampson, Joshua Neil
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2019
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6881075/
https://ncbi.nlm.nih.gov/pubmed/31730655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008490
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы