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Molecular Basis for and chemogenetic Rescue of Comorbidities in GABRG2-Deficient Epilepsies

SUMMARY: OBJECTIVE: GABA(A) receptor subunit gene mutations are significant causes of epilepsy, which are often accompanied with various neuropsychiatric comorbidities, but the underlying mechanisms are unclear. It has been suggested that the comorbidities are caused by seizures as they often presen...

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Dettagli Bibliografici
Pubblicato in:Epilepsia
Autori principali: Zhang, Chun-Qing, McMahon, Bryan, Dong, Huancheng, Warner, Timothy, Shen, Wangzhen, Gallagher, Martin, Macdonald, Robert L., Kang, Jing-Qiong
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6880653/
https://ncbi.nlm.nih.gov/pubmed/31087664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.15160
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