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Molecular Basis for and chemogenetic Rescue of Comorbidities in GABRG2-Deficient Epilepsies

SUMMARY: OBJECTIVE: GABA(A) receptor subunit gene mutations are significant causes of epilepsy, which are often accompanied with various neuropsychiatric comorbidities, but the underlying mechanisms are unclear. It has been suggested that the comorbidities are caused by seizures as they often presen...

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Detalhes bibliográficos
Publicado no:Epilepsia
Main Authors: Zhang, Chun-Qing, McMahon, Bryan, Dong, Huancheng, Warner, Timothy, Shen, Wangzhen, Gallagher, Martin, Macdonald, Robert L., Kang, Jing-Qiong
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6880653/
https://ncbi.nlm.nih.gov/pubmed/31087664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.15160
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