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Molecular Basis for and chemogenetic Rescue of Comorbidities in GABRG2-Deficient Epilepsies

SUMMARY: OBJECTIVE: GABA(A) receptor subunit gene mutations are significant causes of epilepsy, which are often accompanied with various neuropsychiatric comorbidities, but the underlying mechanisms are unclear. It has been suggested that the comorbidities are caused by seizures as they often presen...

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Détails bibliographiques
Publié dans:Epilepsia
Auteurs principaux: Zhang, Chun-Qing, McMahon, Bryan, Dong, Huancheng, Warner, Timothy, Shen, Wangzhen, Gallagher, Martin, Macdonald, Robert L., Kang, Jing-Qiong
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6880653/
https://ncbi.nlm.nih.gov/pubmed/31087664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.15160
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