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Molecular Basis for and chemogenetic Rescue of Comorbidities in GABRG2-Deficient Epilepsies

SUMMARY: OBJECTIVE: GABA(A) receptor subunit gene mutations are significant causes of epilepsy, which are often accompanied with various neuropsychiatric comorbidities, but the underlying mechanisms are unclear. It has been suggested that the comorbidities are caused by seizures as they often presen...

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Bibliographic Details
Published in:Epilepsia
Main Authors: Zhang, Chun-Qing, McMahon, Bryan, Dong, Huancheng, Warner, Timothy, Shen, Wangzhen, Gallagher, Martin, Macdonald, Robert L., Kang, Jing-Qiong
Format: Artigo
Language:Inglês
Published: 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6880653/
https://ncbi.nlm.nih.gov/pubmed/31087664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.15160
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