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Tau Misfolding Efficiently Propagates between Individual Intact Hippocampal Neurons

Neurofibrillary tangles, formed of misfolded, hyperphosphorylated tau protein, are a pathological hallmark of several neurodegenerations, including Alzheimer's disease. Tau pathology spreads between neurons and propagates misfolding in a prion-like manner throughout connected neuronal circuits....

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Hallinan, Grace I., Vargas-Caballero, Mariana, West, Jonathan, Deinhardt, Katrin
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6880463/
https://ncbi.nlm.nih.gov/pubmed/31658988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1590-19.2019
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