Accumulation of damaged mitochondria in alveolar macrophages with reduced OXPHOS related gene expression in IPF

BACKGROUND: Impaired mitochondria homeostasis and function are established hallmarks of aging and increasing evidence suggests a link with lung fibrosis. Mitochondria homeostasis may be also affected in alveolar macrophages (AMs) in idiopathic pulmonary fibrosis (IPF). In this study, we used broncho...

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Dades bibliogràfiques
Publicat a:Respir Res
Autors principals: Tsitoura, Eliza, Vasarmidi, Eirini, Bibaki, Eleni, Trachalaki, Athina, Koutoulaki, Chara, Papastratigakis, George, Papadogiorgaki, Sevasti, Chalepakis, George, Tzanakis, Nikos, Antoniou, Katerina M.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6880424/
https://ncbi.nlm.nih.gov/pubmed/31775876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-019-1196-6
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