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Heat shock pretreatment improves mesenchymal stem cell viability by heat shock proteins and autophagy to prevent cisplatin-induced granulosa cell apoptosis

BACKGROUND: Bone marrow mesenchymal stem cells (BMSCs) can partially repair chemotherapy-induced ovarian damage. However, low survival rate after transplantation hampers the therapeutic efficiency of BMSCs. Heat shock pretreatment (HSP) effectively improves the cell survival. This study attempted to...

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Bibliographische Detailangaben
Veröffentlicht in:Stem Cell Res Ther
Hauptverfasser: Wang, Qing, Li, Xinran, Wang, Qingru, Xie, Jiaxin, Xie, Chuhai, Fu, Xiafei
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6880355/
https://ncbi.nlm.nih.gov/pubmed/31771642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-019-1425-4
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