Genetic and clinical characterization of BRCA-associated hereditary breast and ovarian cancer in Navarra (Spain)

BACKGROUND: Genetic testing for BRCA1/2 genes is widely used as a strategy to reduce incidence and morbidity of hereditary breast and ovarian cancer (HBOC). The purpose of this study is to analyse the demographic and molecular characteristics of BRCA germline mutations in Navarra, Spain, and to inve...

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Vydáno v:BMC Cancer
Hlavní autoři: Ruiz de Sabando, Ainara, Urrutia Lafuente, Edurne, García-Amigot, Fermín, Alonso Sánchez, Angel, Morales Garofalo, Lourdes, Moreno, Sira, Ardanaz, Eva, Ramos-Arroyo, Maria A.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6880350/
https://ncbi.nlm.nih.gov/pubmed/31771539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-6277-x
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